In addition to these standard analyses, BioSpring also offers a variety of broader analyses for special issues. A few (but not exhaustive list) of these are:

• Content determination
• Determination of extinction coefficient
• Salt content
• pH value
• Conductivity
• Tm value
• Differential scanning calorimetry (DSC)
• Solvent residue
• Water content
• Various HPLC analysis techniques
• ESI-MS
• MALDI-MS
• LC-MS
• PO/PS content
• Sequencing
• Endotoxin content
• Total microbial count

Please note that we need additional material for each analysis. This means the final yield of your synthesis will be reduced. For some analyses, up to 200 mg of your oligonucleotide are needed.
 

We normally ship oligonucleotides after lyophilisation (lyophilized). The extent of the analyses delivered with the product depends on the order. For example, the OEX package for oligonucleotides at least 50 base pairs in length always includes an IEX analysis of the end product and an exact indication of the amount being shipped. If you should have specific wishes regarding the analyses, please speak with us directly or make a note of these in your order. Please understand that, depending on the type of analysis, we have to adjust the size of the synthesis, the type of purification and thus the price of your product. This flexibility naturally also applies to the way in which we deliver your order; we will be glad to ship your synthesis product in solute and/or aliquoted form if you so desire.

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BioSpring Oligonucleotides

The Oligo Company
Expertise
Flexibility
Synthesis
Components of synthesis
Separation
Purification
Finishing treatment
Standard analysis
Additional analyses
Complex oligonucleotides
Superstructures