To Homepage

Select your language

Die Inhalte dieser Seite sind auch auf Deutsch verfügbar.

Auf Deutsch ansehen
Superior Quality for high-impact research Nucleic Acids for Research and Development

Nucleic Acids for R&D

BioSpring is committed to providing the highest quality, comparable, and scalable manufacturing processes across all grades. With over a hundred thousand successfully synthesized nucleic acids in the past decade alone, BioSpring’s manufacturing platform is designed for the quality manufacture of your unique sequences.

Our preclinical and diagnostic manufacturing teams specialize in small-scale material starting from nmol/μg up to mid-scale manufacture of several grams. Should your program require additional material, our interdivisional cooperation allows for seamless upscaling up to kg scales. Beyond synthesis, we offer expert analytical services and project support from inquiry through delivery.

Several prerequisites contribute to our product quality

  • High-quality raw materials from selected suppliers
  • Optimized & controlled manufacturing processes executed by highly qualified, trained professionals
  • Continuous monitoring of in-process controls & final products by our Quality Control Department
  • Advanced technologies for nucleic acid analysis

Service Overview

Experts in highly modified, complex molecules

  • siRNAs, ASOs, ssDNAs, & more
  • Simultaneous manufacturing of >400 sequences
  • Variety of customizable synthesizer platforms
  • Screening libraries (e.g., 96-well plate format) & randomized oligonucleotide libraries
  • New_Button_website.pngIVT mRNA with fully customizable capping, poly(A) tail length, & modifications up to 7 kb (or longer)

Customized Solutions

We tailor our services to your needs and customize our process for the best possible outcomes. Clients may request custom starting materials and personalize the manufacturing and release testing scope. Flexible delivery options and aliquoting services are available, along with services such as cleaning in place (CIP). Additionally, we provide comprehensive analytical services (e.g., LC-MA and endotoxin testing) to meet your needs.

Advanced Technology

Select from a large portfolio of modifications and a variety of customizable synthesizer platforms. Our ultramodern technology accommodates long sequences and conjugation/liquid chemistry.